Publikationen

Chiriac MT, Hracsko Z, Günther C, Gonzalez-Acera M, Atreya R, Stolzer I, Wittner L, Dressel A, Schickedanz L, Gamez-Belmonte R, Erkert L, Hundorfean G, Zundler S, Rath T, Vetrano S, Danese S, Sturm G, Trajanoski Z, Kühl AA, Siegmund B, Hartmann A, Wirtz S, Siebler J, Finotto S, Becker C, Neurath MF: (2024) IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling. Gut. 2024;73(2): 282-297
Papadopoulos NG, Akdis C, Akdis M, Damialis A, Esposito G, Fergadiotou I, Goroncy C, Guitton P, Gotua M, Erotokritou K, Jartti T, Murray C, Nenes A, Nikoletseas S, Finotto S, Pandis SN, Ramiconi V, Simpson A, Soudunsaari A, Stårbröst A, Staiano M, Varriale A, Xepapadaki P, Zuberbier T, Annesi-Maesano I, SynAir-G Consortium , Papadopoulos NG, Xepapadaki P, Stergiou I, Kritikou M, Taka S, Mageiros L, Pachi K, Stamou E, Annesi-Maesano I, Caimmi D, Tanno LK, Demoly P, Jartti T, Elenius V, Finotto S, Kropf L, Stahlbrost A, Habibipour A, Nikoletseas S, Filios G, Tzamalis P, Raptopoulos C, Markantonatos D, Kalioras F, Kapetanidis P, Damialis A, Varriale A, D'Auria S, Staiano M, Pennacchio A, Capo A, Montagnese C, Gotua M, Abramidze T, Rukhadze M, Pandis SN, Dovrou E, Goroncy C, Kelnberger S, Ramiconi V, Papotto A, Chaslaridis P, Rossi A, Zuberbier T, van Hofman I, Chadha Y, Fergadiotou I, Kampa M, Kouloumbis M, Loupos K, Kakouris T, Antoniou S, Priniotaki G, Soudunsaari A, Järvinen N, Guitton P, Larigaldie P, Hadjiantonis A, Giusti A, Erotokritou K, Hadjantonis A, Papadopoulos A, Demosthenous P, Esposito G, Schena F, Randon M, Nenes A, Akdis C, Akdis M, Pat Y, Murray C, Simpson A: (2024) Addressing adverse synergies between chemical and biological pollutants at schools-The 'SynAir-G' hypothesis. Allergy. 2024;79(2): 294-301
Thome CD, Tausche P, Hohenberger K, Yang Z, Krammer S, Trufa DI, Sirbu H, Schmidt J, Finotto S: (2024) Short-chain fatty acids induced lung tumor cell death and increased peripheral blood CD4+ T cells in NSCLC and control patients ex vivo. Front Immunol. 2024;15():
Schenzel A, Geiger A, Nendel E, Yang Z, Krammer S, Leberle A, Brunst AK, Trump S, Mittler S, Rauh M, Geppert CI, Tausche P, Hohenberger K, Rieker RJ, Schieweck O, Zundler S, Finotto S: (2024) Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma. Front Nutr. 2024;11():
Gao YD, Xepapadaki P, Cui YW, Stanic B, Maurer DJ, Bachert C, Zhang N, Finotto S, Chalubinski M, Lukkarinen H, Passioti M, Graser A, Jartti T, Kowalski M, Ogulur I, Shi ZW, Akdis M, Papadopoulos NG, Akdis CA: (2023) Effect of Haemophilus influenzae, Streptococcus pneumoniae and influenza vaccinations on infections, immune response and asthma control in preschool children with asthma. Allergy. 2023;78(6): 1473-1488
Hartmann P, Trufa DI, Hohenberger K, Tausche P, Trump S, Mittler S, Geppert CI, Rieker RJ, Schieweck O, Sirbu H, Hartmann A, Finotto S: (2023) Contribution of serum lipids and cholesterol cellular metabolism in lung cancer development and progression. Sci Rep. 2023;13(1):
Rovira Rubió J, Megremis S, Pasioti M, Lakoumentas J, Constantinides B, Xepapadaki P, Bachert C, Finotto S, Jartti T, Andreakos E, Stanic B, Akdis CA, Akdis M, Papadopoulos NG: (2023) Respiratory virome profiles reflect antiviral immune responses. Allergy. 2023;78(5): 1258-1268
Ullrich KA, Derdau J, Baltes C, Battistella A, Rosso G, Uderhardt S, Schulze LL, Liu LJ, Dedden M, Spocinska M, Kainka L, Kubánková M, Müller TM, Schmidt NM, Becker E, Ben Brahim O, Atreya I, Finotto S, Prots I, Wirtz S, Weigmann B, López-Posadas R, Atreya R, Ekici AB, Lautenschläger F, Guck J, Neurath MF, Zundler S: (2023) IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells. Gut. 2023;72(11): 2081-2094
Megremis S, Constantinides B, Xepapadaki P, Yap CF, Sotiropoulos AG, Bachert C, Finotto S, Jartti T, Tapinos A, Vuorinen T, Andreakos E, Robertson DL, Papadopoulos NG: (2023) Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma. Sci Rep. 2023;13(1):
Bose T, Medina-Contreras O, Fernandez C, Finotto S: (2023) Editorial: Women in mucosal immunity. Front Immunol. 2023;14():
Maurer DJ, Liu C, Xepapadaki P, Stanic B, Bachert C, Finotto S, Gao YD, Graser A, Jartti T, Kistler W, Kowalski M, Lukkarinen H, Pasioti M, Tan G, Villiger M, Zhang L, Zhang N, Akdis M, Papadopoulos NG, Akdis CA: (2022) Physical activity in asthma control and its immune modulatory effect in asthmatic preschoolers. Allergy. 2022;77(4): 1216-1230
Finotto S, Jartti T, Johnston SL: (2022) Editorial: Type I and Type III Interferon Immune Responses in Asthma. Front Immunol. 2022;12():
Krammer S, Yang Z, Zimmermann T, Xepapadaki P, Geppert CI, Papadopoulos NG, Finotto S: (2022) An Immunoregulatory Role of Interleukin-3 in Allergic Asthma. Front Immunol. 2022;13():
Gähler A, Trufa DI, Chiriac MT, Tausche P, Hohenberger K, Brunst AK, Rauh M, Geppert CI, Rieker RJ, Krammer S, Leberle A, Neurath MF, Sirbu H, Hartmann A, Finotto S: (2022) Glucose-Restricted Diet Regulates the Tumor Immune Microenvironment and Prevents Tumor Growth in Lung Adenocarcinoma. Front Oncol. 2022;12():
Heim L, Yang Z, Tausche P, Hohenberger K, Chiriac MT, Koelle J, Geppert CI, Kachler K, Miksch S, Graser A, Friedrich J, Kharwadkar R, Rieker RJ, Trufa DI, Sirbu H, Neurath MF, Kaplan MH, Finotto S: (2022) IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer. Front Immunol. 2022;13():
Kölle J, Zimmermann T, Kiefer A, Rieker RJ, Xepapadaki P, Zundler S, Papadopoulos NG, Finotto S: (2022) Targeted deletion of Interleukin-3 results in asthma exacerbations. iScience. 2022;25(6):
Krammer S, Yang Z, Mitländer H, Grund JC, Trump S, Mittler S, Zirlik S, Finotto S: (2022) Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells. Cells. 2022;12(1):
Krug J, Kiefer A, Koelle J, Vuorinen T, Xepapadaki P, Stanic B, Chiriac M, Akdis M, Zimmermann T, Papadopoulos NG, Finotto S: (2021) TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma. Eur Respir J. 2021;57(5):
Andreev D, Liu M, Kachler K, Llerins Perez M, Kirchner P, Kölle J, Gießl A, Rauber S, Song R, Aust O, Grüneboom A, Kleyer A, Cañete JD, Ekici A, Ramming A, Finotto S, Schett G, Bozec A: (2021) Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis. Ann Rheum Dis. 2021;80(4): 451-468
Krammer S, Sicorschi Gutu C, Grund JC, Chiriac MT, Zirlik S, Finotto S: (2021) Regulation and Function of Interferon-Lambda (IFNλ) and Its Receptor in Asthma. Front Immunol. 2021;12():
Li N, Mirzakhani H, Kiefer A, Koelle J, Vuorinen T, Rauh M, Yang Z, Krammer S, Xepapadaki P, Lewandowska-Polak A, Lukkarinen H, Zhang N, Stanic B, Zimmermann T, Kowalski ML, Jartti T, Bachert C, Akdis M, Papadopoulos NG, Raby BA, Weiss ST, Finotto S: (2021) Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma. iScience. 2021;24(10):
Yang Z, Mitländer H, Vuorinen T, Finotto S: (2021) Mechanism of Rhinovirus Immunity and Asthma. Front Immunol. 2021;12():
Jartti T, Liimatainen U, Xepapadaki P, Vahlberg T, Bachert C, Finotto S, Kowalski ML, Sobanska A, Lukkarinen H, Pasioti M, Vuorinen T, Zhang N, Zimmermann T, Papadopoulos NG: (2021) Clinical correlates of rhinovirus infection in preschool asthma. Allergy. 2021;76(1): 247-254
Yang ZQ, Mitlaender H, Vuorinen T, Finotto S: (2021) Mechanism of Rhinovirus Immunity and Asthma (vol 12, 731846, 2021) Front Immunol. 2021;12():
Krammer S, Yang Z, Gutu CS, Grund J, Mitlaender H, Zirlik S, Finotto S: (2021) Expression of IFN lambda and its receptor in human adult asthma cohort AZCRA Allergy. 2021;76 Suppl 110(): 109-109
Finotto S, Tausche P, Hohenberger K, Neurath L, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Finotto S: (2021) Tumour immune evasion mechanism in non-small cell lung cancer by inducing Blimp-1 in CD4+CD25+Foxp-3+T regulatory cells J Immunol. 2021;206 Suppl 1():
Gaehler A, Hohenberger K, Tausche P, Chiriac MT, Rauh M, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Finotto S: (2021) Effects of glucose concentration in the tumor microenvironment on Non Small Lung Cancer (NSCLC) Progression J Immunol. 2021;206 Suppl 1():
Hohenberger K, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Finotto S: (2021) IL-2 decreased PU.1 and PD-1 expression in NK-cells in NSCLC patients J Immunol. 2021;206 Suppl 1():
Tausche P, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Finotto S: (2021) Lung tumor immune evasion mechanism in Non-small cell lung cancer (NSCLC) targets pSTAT5 in CD4+CD25+FoxP3-T effector cells J Immunol. 2021;206 Suppl 1():
Xepapadaki P, Korovessi P, Bachert C, Finotto S, Jartti T, Lakoumentas J, Kowalski ML, Lewandowska-Polak A, Lukkarinen H, Zhang N, Zimmermann T, Papadopoulos NG: (2020) Evolution of Airway Inflammation in Preschoolers with Asthma-Results of a Two-Year Longitudinal Study. J. Clin. Med.. 2020;9(1):
Neurath L, Trufa D, Geppert C, Rieker R, Sirbu H, Finotto S: (2020) Late Breaking Abstract - Induction of the transcriptional repressor B lymphocytes-induced maturation protein-1 (Blimp-1) in lung cancer Eur Respir J. 2020;56 Suppl 64():
Kölle J, Haag P, Vuorinen T, Alexander K, Rauh M, Zimmermann T, Papadopoulos NG, Finotto S: (2020) Respiratory infections regulated blood cells IFN-β-PD-L1 pathway in pediatric asthma. Immun Inflamm Dis. 2020;8(3): 310-319
Krammer S, Li NN, Yang ZQ, Koelle J, Geppert CI, Rieker RJ, Graham G, Finotto S: (2020) Late Breaking Abstract - The Role of the chemokine receptor CCR3 in House Dust Mite (HDM) induced experimental asthma Eur Respir J. 2020;56 Suppl 64():
Jakobi M, Kiefer A, Mirzakhani H, Rauh M, Zimmermann T, Xepapadaki P, Stanic B, Akdis M, Papadopoulos NG, Raby BA, Weiss ST, Finotto S: (2020) Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma. Immun Inflamm Dis. 2020;8(4): 704-712
Koelle J, Vuorinen T, Kiefer A, Zimmermann T, Xepapadaki P, Rieker R, Papadopoulos NG, Finotto S: (2020) The role of interleukin 3 (IL3) in allergic asthma Allergy. 2020;75 Suppl 109(): 163-163
Krug J, Koelle J, Kiefer A, Vuorinen T, Xepapadaki P, Stanic B, Chiriac M, Akdis M, Zimmermann T, Papadopoulos NG, Finotto S: (2020) The role of interferon type I and type III receptors in rhinovirus induced allergic asthma Allergy. 2020;75 Suppl 109(): 277-278
Yang ZQ, Li NN, Koelle J, Rieker RJ, Finotto S: (2020) Late Breaking Abstract - GATA-3 in lung CD4+T cells drives Interleukin-10 deficiency-induced lung inflammation in asthma Eur Respir J. 2020;56 Suppl 64():
Li N, Koelle J, Kiefer A, Xepapadaki P, Kowalski ML, Bachert C, Jartti T, Vuorinen T, Lewandowska-Polak A, Zhang N, Lukkarinen H, Zimmermann T, Akdis M, Papadopoulos NG, Finotto S: (2020) The role of regulated on activation, normal T cell expressed and secreted (RANTES) in allergic asthma Allergy. 2020;75 Suppl 109(): 164-165
Yang Z, Li N, Koelle J, Rieker RJ, Finotto S: (2020) The role of interleukin-10 in asthma Allergy. 2020;75 Suppl 109(): 369-369
Jakobi M, Mirzakahni H, Kiefer A, Rauh M, Zimmermann T, Papadopoulos NG, Raby BA, Weiss ST, Finotto S: (2020) Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma Allergy. 2020;75 Suppl 109(): 181-182
Hohenberger K, Trufa D, Gebbert C, Rieker R, Sirbu H, Finotto S: (2020) The role of the transcription factor PU.1 in lung cancer Eur Respir J. 2020;56 Suppl 64():
Tausche P, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Neurath-Finotto S: (2020) Role of phosphorylated Signal Transducer and Activator of Transcription 5 (pSTAT5) in non-small cell lung cancer (NSCLC) Eur Respir J. 2020;56 Suppl 64():
Liu M, Andreev D, Kachler K, Koelle J, Rauber S, Ramming A, Finotto S, Schett G, Bozec A: (2020) ALLERGIC ASTHMA INDUCES THE ACCUMULATION OF SYNOVIAL RESIDENT EOSINOPHILS, TRIGGERING THE RESOLUTION OF INFLAMMATORY ARTHRITIS Ann Rheum Dis. 2020;79 Suppl 1(): 86-86
Xepapadaki P, Korovessi P, Bachert C, Finotto S, Jartti T, Lakoumentas J, Kowalski ML, Lewandowska-Polak A, Lukkarinen H, Zhang N, Zimmermann T, Papadopoulos NG: (2020) Evolution of airway inflammation in preschoolers with asthma-results of a two-year longitudinal study Allergy. 2020;75 Suppl 109(): 399-399
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A: (2019) PU.1 controls fibroblast polarization and tissue fibrosis. Nature. 2019;566(7744): 344-349
Finotto S: (2019) B lymphocyte-induced maturation protein 1 (Blimp-1), a negative regulator of TH9 development, orchestrates the resolution of airway inflammation in patients with allergic asthma. J Allergy Clin Immunol. 2019;143(3): 937-939
Koch S, Knipfer L, Kölle J, Mirzakhani H, Graser A, Zimmermann T, Kiefer A, Melichar VO, Rascher W, Papadopoulos NG, Rieker RJ, Raby BA, Weiss ST, Wirtz S, Finotto S: (2019) Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2). Sci Rep. 2019;9(1):
Sopel N, Kölle J, Dumendiak S, Koch S, Reichel M, Rhein C, Kornhuber J, Finotto S: (2019) Immunoregulatory role of acid sphingomyelinase in allergic asthma. Immunology. 2019;156(4): 373-383
Heim L, Kachler K, Siegmund R, Trufa DI, Mittler S, Geppert CI, Friedrich J, Rieker RJ, Sirbu H, Finotto S: (2019) Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer. Br J Cancer. 2019;120(9): 903-912
Finotto S: (2019) Resolution of allergic asthma. Semin Immunopathol. 2019;41(6): 665-674
Koelle J, Haag P, Vuorinen T, Kiefer A, Papadopoulos NG, Finotto S: (2019) Allergen and rhinovirus (RV) regulation of PD-L1/PD1 in allergic asthma Allergy. 2019;74 Suppl 106(): 4-5
Koelle J, Haag P, Vuorinen T, Kiefer A, Zimmermann T, Papadopoulos NG, Finotto S: (2018) CTLA4 induction by Rhinovirus (RV) in pediatric asthma Allergy. 2018;73(): 301-302
Kachler K, Holzinger C, Trufa DI, Sirbu H, Finotto S: (2018) The role of Foxp3 and Tbet co-expressing Treg cells in lung carcinoma. Oncoimmunology. 2018;7(8):
Xepapadaki P, Bachert C, Finotto S, Jartti T, Konstantinou GN, Kiefer A, Kowalski M, Lewandowska-Polak A, Lukkarinen H, Roumpedaki E, Sobanska A, Sintobin I, Vuorinen T, Zhang N, Zimmermann T, Papadopoulos NG: (2018) Contribution of repeated infections in asthma persistence from preschool to school age: Design and characteristics of the PreDicta cohort. Pediatr Allergy Immunol. 2018;29(4): 383-393
Heim L, Friedrich J, Engelhardt M, Trufa DI, Geppert CI, Rieker RJ, Sirbu H, Finotto S: (2018) NFATc1 Promotes Antitumoral Effector Functions and Memory CD8+ T-cell Differentiation during Non-Small Cell Lung Cancer Development. Cancer Res. 2018;78(13): 3619-3633
Megremis S, Niespodziana K, Cabauatan C, Xepapadaki P, Kowalski ML, Jartti T, Bachert C, Finotto S, West P, Stamataki S, Lewandowska-Polak A, Lukkarinen H, Zhang N, Zimmermann T, Stolz F, Neubauer A, Akdis M, Andreakos E, Valenta R, Papadopoulos NG: (2018) Rhinovirus Species-Specific Antibodies Differentially Reflect Clinical Outcomes in Health and Asthma. Am J Respir Crit Care Med. 2018;198(12): 1490-1499
Friedrich J, Heim L, Trufa DI, Sirbu H, Rieker RJ, Chiriac MT, Finotto S: (2018) STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC. Oncotarget. 2018;9(98): 37157-37172
Haag P, Sharma H, Rauh M, Zimmermann T, Vuorinen T, Papadopoulos NG, Weiss ST, Finotto S: (2018) Soluble ST2 regulation by rhinovirus and 25(OH)-vitamin D3 in the blood of asthmatic children. Clin Exp Immunol. 2018;193(2): 207-220
Bergauer A, Sopel N, Kroß B, Vuorinen T, Xepapadaki P, Weiss ST, Blau A, Sharma H, Kraus C, Springel R, Rauh M, Mittler S, Graser A, Zimmermann T, Melichar VO, Kiefer A, Kowalski ML, Sobanska A, Jartti T, Lukkarinen H, Papadopoulos NG, Finotto S: (2017) IFN-?/IFN-? responses to respiratory viruses in paediatric asthma. Eur Respir J. 2017;49(2):
Eisenhut F, Heim L, Trump S, Mittler S, Sopel N, Andreev K, Ferrazzi F, Ekici AB, Rieker R, Springel R, Assmann VL, Lechmann M, Koch S, Engelhardt M, Warnecke C, Trufa DI, Sirbu H, Hartmann A, Finotto S: (2017) FAM13A is associated with non-small cell lung cancer (NSCLC) progression and controls tumor cell proliferation and survival. Oncoimmunology. 2017;6(1): e1256526
Hentschke I, Graser A, Melichar VO, Kiefer A, Zimmermann T, Kroß B, Haag P, Xepapadaki P, Papadopoulos NG, Bogdan C, Finotto S: (2017) IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma. Sci Rep. 2017;7(): 43426
Bergauer A, Sopel N, Kroß B, Vuorinen T, Xepapadaki P, Weiss ST, Blau A, Sharma H, Kraus C, Springel R, Rauh M, Mittler S, Graser A, Zimmermann T, Melichar VO, Kiefer A, Kowalski ML, Sobanska A, Jartti T, Lukkarinen H, Papadopoulos NG, Finotto S: (2017) Rhinovirus species/genotypes and interferon-?: subtypes, receptor and polymorphisms - missing pieces of the puzzle of childhood asthma? Eur Respir J. 2017;49(3):
Koch S, Sopel N, Finotto S: (2017) Th9 and other IL-9-producing cells in allergic asthma. Semin Immunopathol. 2017;39(1): 55-68
Hentschke I, Graser A, Melichar VO, Kiefer A, Zimmermann T, Kroß B, Haag P, Xepapadaki P, Papadopoulos NG, Bogdan C, Finotto S: (2017) Corrigendum: IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma. Sci Rep. 2017;7(): 46897
Bielor C, Sopel N, Maier A, Blau A, Sharma H, Vuorinen T, Kroß B, Mittler S, Graser A, Mousset S, Melichar VO, Kiefer A, Zimmermann T, Springel R, Holzinger C, Trump S, Taka S, Papadopoulos NG, Weiss ST, Finotto S: (2017) Role of TGF-β in anti-rhinovirus immune responses in asthmatic patients. J Allergy Clin Immunol. 2017;140(1): 283-286.e10
Sopel N, Pflaum A, Kölle J, Finotto S: (2017) The Unresolved Role of Interferon-λ inAsthma Bronchiale. Front Immunol. 2017;8():
Kachler K, Bailer M, Heim L, Schumacher F, Reichel M, Holzinger CD, Trump S, Mittler S, Monti J, Trufa DI, Rieker RJ, Hartmann A, Sirbu H, Kleuser B, Kornhuber J, Finotto S: (2017) Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma. Cancer Res. 2017;77(21): 5963-5976
Bergauer A, Sopel N, Kroß B, Vuorinen T, Xepapadaki P, Weiss ST, Blau A, Sharma H, Kraus C, Springel R, Rauh M, Mittler S, Graser A, Zimmermann T, Melichar VO, Kiefer A, Kowalski ML, Sobanska A, Jartti T, Lukkarinen H, Papadopoulos NG, Finotto S: (2017) IFN-α/IFN-λ responses to respiratory viruses in paediatric asthma. Eur Respir J. 2017;49(3):
Finotto S, Bielor C, Sopel N, Vuorinen T, Melichar VO, Kiefer A, Zimmermann T, Papadopoulos NG, Weiss ST: (2017) Tgf-beta regulation and regulated anti-rhinovirus (RV) immune responses in asthma Allergy. 2017;72(): 107-107
Finotto S, Bergauer A, Sopel N, Kross B, Vuorinen T, Weiss ST, Rauh M, Melichar VO, Kiefer A, Zimmermann T, Ml K, Jartti T, Lukkarinen H, Papadopoulos NG: (2017) Type 1 interferon alpha (IFN-a) regulation by respiratory viruses in pediatric asthma Allergy. 2017;72(): 106-107
Vahl JM, Friedrich J, Mittler S, Trump S, Heim L, Kachler K, Balabko L, Fuhrich N, Geppert CI, Trufa DI, Sopel N, Rieker R, Sirbu H, Finotto S: (2017) Interleukin-10-regulated tumour tolerance in non-small cell lung cancer. Br J Cancer. 2017;117(11): 1644-1655
Koch S, Graser A, Mirzakhani H, Zimmermann T, Melichar VO, Wölfel M, Croteau-Chonka DC, Raby BA, Weiss ST, Finotto S: (2016) Increased expression of nuclear factor of activated T cells 1 drives IL-9-mediated allergic asthma. J Allergy Clin Immunol. 2016;137(6): 1898-1902.e7
Neurath MF, Finotto S: (2016) IL-9 signaling as key driver of chronic inflammation in mucosal immunity. Cytokine Growth Factor Rev. 2016;29(): 93-9
Sopel N, Graser A, Mousset S, Finotto S: (2016) The transcription factor BATF modulates cytokine-mediated responses in T cells. Cytokine Growth Factor Rev. 2016;30(): 39-45
Graser A, Ekici AB, Sopel N, Melichar VO, Zimmermann T, Papadopoulos NG, Taka S, Ferrazzi F, Vuorinen T, Finotto S: (2016) Rhinovirus inhibits IL-17A and the downstream immune responses in allergic asthma. Mucosal Immunol. 2016;9(5): 1183-92
Glanville N, Peel TJ, Schröder A, Aniscenko J, Walton RP, Finotto S, Johnston SL: (2016) Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection. PLoS Pathog. 2016;12(9): e1005913
Friedrich JMMM, Heim L, Springel R, Mittler S, Gafencu D, Hartmann A, Sirbu H, Finotto S: (2016) The role of Signal Transducer and Activator of Transcription protein 5 (STAT5) in non-small cell lung cancer (NSCLC) J Immunol. 2016;196 1(): -
Heim L, Andreev K, Balabko L, Trufa DI, Sirbu H, Hartmann A, Finotto S: (2016) The role of STAT3 (signal transducer and activator of transcription 3) in non-small cell lung cancer (NSCLC) J Immunol. 2016;196 1(): -
Andreev K, Trufa DI, Siegemund R, Rieker R, Hartmann A, Schmidt J, Sirbu H, Finotto S: (2016) Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma. Br J Cancer. 2016;115(9):
Reppert S, Zinser E, Holzinger C, Sandrock L, Koch S, Finotto S: (2015) NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis. Eur J Immunol. 2015;45(5): 1426-40
Koch S, Finotto S: (2015) Role of Interferon-? in Allergic Asthma. J Innate Immun. 2015;7(3): 224-30
Böhm L, Maxeiner J, Meyer-Martin H, Reuter S, Finotto S, Klein M, Schild H, Schmitt E, Bopp T, Taube C: (2015) IL-10 and regulatory T cells cooperate in allergen-specific immunotherapy to ameliorate allergic asthma. J Immunol. 2015;194(3): 887-97
Andreev K, Denis Iulian Trufa I, Siegemund R, Rieker R, Hartmann A, Schmidt J, Sirbu H, Finotto S: (2015) Impaired T-bet-pSTAT1? and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma. Br J Cancer. 2015;113(6): 902-13
Koch S, Reppert S, Finotto S: (2015) NFATc1 deletion in T lymphocytes inhibits the allergic trait in a murine model of asthma. Clin Exp Allergy. 2015;45(8): 1356-66
Graser A, Ekici AB, Melichar VO, Zimmermann T, Papadopoulos NG, Taka S, Ferrazzi F, Vuorinen T, Finotto S: (2015) The anti-viral properties of IL-17A in allergic asthma Cytokine. 2015;76(1): 96-96
Sopel N, Ubel C, Finotto S: (2015) T-helper 1 and regulatory T cell mediated responses are influenced by BATF in a setting of murine experimental asthma Cytokine. 2015;76(1): 96-96
Heim L, Finotto S: (2015) The role of STAT3 (Signal Transducer and Activator of Transcription protein-3) in non-small cell lung cancer (NSCLC) Cytokine. 2015;76(1): 97-97
Roumpedaki E, Karantoumanis D, Xepapadaki P, Sintobin I, Bachert C, Lukkarinen H, Jartti T, Zimmerman T, Finotto S, Sobanska A, Kowalski M, Papadopoulos NG: (2015) Severity of asthma symptoms, lung function and airway inflammation in the PreDicta cohort of preschool-age children with asthma Allergy. 2015;70(): 512-513
Übel C, Sopel N, Graser A, Hildner K, Reinhardt C, Zimmermann T, Rieker RJ, Maier A, Neurath MF, Murphy KM, Finotto S: (2014) The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma. J Allergy Clin Immunol. 2014;133(1): 198-206.e9
Schicht M, Rausch F, Finotto S, Mathews M, Mattil A, Schubert M, Koch B, Traxdorf M, Bohr C, Worlitzsch D, Brandt W, Garreis F, Sel S, Paulsen F, Bräuer L: (2014) SFTA3, a novel protein of the lung: three-dimensional structure, characterisation and immune activation. Eur Respir J. 2014;44(2): 447-56
Balabko L, Andreev K, Burmann N, Schubert M, Mathews M, Trufa DI, Reppert S, Rau T, Schicht M, Sirbu H, Hartmann A, Finotto S: (2014) Increased expression of the Th17-IL-6R/pSTAT3/BATF/Ror?T-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung. Sci Rep. 2014;4(): 7396
Übel C, Graser A, Koch S, Rieker RJ, Lehr HA, Müller M, Finotto S: (2014) Role of Tyk-2 in Th9 and Th17 cells in allergic asthma. Sci Rep. 2014;4(): 5865
Chandran PA, Keller A, Weinmann L, Seida AA, Braun M, Andreev K, Fischer B, Horn E, Schwinn S, Junker M, Houben R, Dombrowski Y, Dietl J, Finotto S, Wölfl M, Meister G, Wischhusen J: (2014) The TGF-?-inducible miR-23a cluster attenuates IFN-? levels and antigen-specific cytotoxicity in human CD8? T cells. J Leukoc Biol. 2014;96(4): 633-45
Sopel N, Uebel C, Graser A, Hildner K, Reinhardt C, Zimmermann T, Rieker RJ, Neurath MF, Murphy KM, Finotto S: (2014) The transcription factor BATF is involved in the regulation of immune responses in allergic asthma Allergy. 2014;69 99(): 617-618
Graser A, Zimmermann T, Papadopoulos NG, Vuorinen T, Finotto S: (2014) IL-17A and its anti-viral properties in allergic asthma Allergy. 2014;69 99(): 590-590
Roumpedaki E, Xepapadaki P, Taprantzi P, Tineke D, Bachert C, Lukkarinen H, Jartti T, Graser A, Zimmermann T, Finotto S, Sobanska A, Kowalski ML, Papadopoulos NG: (2014) Atopy, rhinitis, lung function and inflammation in asthmatic preschoolers and healthy controls Allergy. 2014;69 99(): 576-576
Koch S, Mousset S, Graser A, Reppert S, Übel C, Reinhardt C, Zimmermann T, Rieker R, Lehr HA, Finotto S: (2013) IL-6 activated integrated BATF/IRF4 functions in lymphocytes are T-bet-independent and reversed by subcutaneous immunotherapy. Sci Rep. 2013;3(): 1754
Ubel C, Mousset S, Trufa D, Sirbu H, Finotto S: (2013) Establishing the role of tyrosine kinase 2 in cancer. Oncoimmunology. 2013;2(1): e22840
Roumpedaki E, Xepapadaki P, Doudoulakakis A, Lebessi E, Passioti M, Skevaki C, Taprantzi P, Tsakanikos M, Tsolia M, Dutre T, Bachert C, Lindholm L, Lukkarinen H, Jartti T, Albert F, Graser A, Geissdörfer W, Bogdan C, Zimmermann T, Finotto S, Sobanska A, Kowalski ML, Papadopoulos NG: (2013) Nasopharyngeal bacterial colonization in asthmatic children and healthy controls Allergy. 2013;68 97(): 230-231
Andreev K, Soo-Becker K, Engelhardt M, Koslowski M, Finotto S: (2013) TGF beta-signaling in T cells suppresses Tbet mediated CD4(+) anti-tumor immune responses in a murine model of lung carcinoma J Immunol. 2013;190(): -
Karwot R, Ubel C, Bopp T, Schmitt E, Finotto S: (2012) Increased immunosuppressive function of CD4(+)CD25(+)Foxp3(+)GITR+ T regulatory cells from NFATc2((-/-)) mice controls allergen-induced experimental asthma. Immunobiology. 2012;217(9): 905-11
Andreev K, Graser A, Maier A, Mousset S, Finotto S: (2012) Therapeutical measures to control airway tolerance in asthma and lung cancer. Front Immunol. 2012;3(): 216
Neurath MF, Finotto S: (2012) The emerging role of T cell cytokines in non-small cell lung cancer. Cytokine Growth Factor Rev. 2012;23(6): 315-22
Reppert S, Koch S, Finotto S: (2012) IL-17A is a central regulator of lung tumor growth. Oncoimmunology. 2012;1(5): 783-785
Graser A, Zhivkova N, Finotto S: (2012) Role of IL-17A in airway tolerance in a murine model of asthma J Immunol. 2012;188(): -
Mousset S, Koch S, Finotto S: (2012) Immunotherapy reduces IL-33 and IL-6 expression in the lung of T-bet deficient mice in an experimental model of allergic asthma J Immunol. 2012;188(): -
Hausding M, Tepe M, Ubel C, Lehr HA, Röhrig B, Hohn Y, Pautz A, Eigenbrod T, Anke T, Kleinert H, Erkel G, Finotto S: (2011) Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma. Int Immunol. 2011;23(1): 1-15
Neurath MF, Finotto S: (2011) IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev. 2011;22(2): 83-9
Koltsida O, Hausding M, Stavropoulos A, Koch S, Tzelepis G, Ubel C, Kotenko SV, Sideras P, Lehr HA, Tepe M, Klucher KM, Doyle SE, Neurath MF, Finotto S, Andreakos E: (2011) IL-28A (IFN-?2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease. EMBO Mol Med. 2011;3(6): 348-61
Reppert S, Boross I, Koslowski M, Tureci O, Koch S, Lehr HA, Finotto S: (2011) A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer. Nat Commun. 2011;2(): 600
Atreya R, Mudter J, Finotto S, Mullberg J, Jostock T, Wirtz S, Schutz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schurmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF: (2010) Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo (vol 6, pg 583, 2000) Nat Med. 2010;16(11): 1341-1341
Caucig P, Teschner D, Dinges S, Maxeiner JH, Reuter S, Finotto S, Taube C, von Stebut E: (2010) Dual role of interleukin-1alpha in delayed-type hypersensitivity and airway hyperresponsiveness. Int Arch Allergy Immunol. 2010;152(4): 303-12
Neurath MF, Finotto S: (2009) Translating inflammatory bowel disease research into clinical medicine. Immunity. 2009;31(3): 357-61
Maxeiner JH, Karwot R, Sauer K, Scholtes P, Boross I, Koslowski M, Tureci O, Wiewrodt R, Neurath MF, Lehr HA, Finotto S: (2009) A key regulatory role of the transcription factor NFATc2 in bronchial adenocarcinoma via CD8+ T lymphocytes. Cancer Res. 2009;69(7): 3069-76
Sudowe S, Neufurth M, Montermann E, Scholtes P, Finotto S, Grabbe S, Reske-Kunz A: (2008) Modalities of elicitation of airway hyperresponsiveness by allergen-specific Th1 and Tc1 cells, induced by gene gun-mediated DNA vaccination Allergy. 2008;63 Suppl. (): 509 -
Hohn Y, Renzing A, Montermann E, Scholtes P, Closs E, Finotto S, Bros M, Grabbe S, Reske-Kunz A, Sudowe S: (2008) Co-expression of indoleamine-2, 3-dioxygenase (IDO) after gene gun-mediated DNA vaccination suppresses induction of transgene-specific immune responses Allergy. 2008;63 Suppl. (): 511 -
Karwot R, Maxeiner J, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, Finotto S: (2008) Protective role of NFATc2 in CD8+long lived memory T cells in an allergy model Wien Klin Wochenschr. 2008;120 Suppl.(): 130-131
Zhivkova N, Karwot R, Maxeiner JH, Scholtes P, Soo K, Finotto S: (2008) Antigen-specific immunotherapy inhibited Th2 via GATA-3 and Th17 cells in an allergic asthma model Wien Klin Wochenschr. 2008;120 Suppl.(): 28-28
Soo K, Karwot R, Maxeiner JH, Scholtes P, Boross I, Zhivkova N, Lehr HA, Koslowski M, Wiewrodt R, Tureci O, Finotto S: (2008) The role of TGF beta signaling in murine models of lung cancer Wien Klin Wochenschr. 2008;120 Suppl.(): 88-89
Tepe M, Scholtes P, Boross I, Karwot R, Maxeiner JH, Hausding M, Wiewrodt R, Schmitt E, Lehr HA, Finotto S: (2008) The regulatory control of IL-2 signal transduction in a murine model of lung tumor Wien Klin Wochenschr. 2008;120 Suppl.(): 89-89
Sauer KA, Maxeiner JH, Karwot R, Scholtes P, Lehr HA, Birkenbach M, Blumberg RS, Finotto S: (2008) Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells. J Immunol. 2008;181(9): 6148-57
Doganci A, Karwot R, Maxeiner JH, Scholtes P, Schmitt E, Neurath MF, Lehr HA, Ho IC, Finotto S: (2008) IL-2 receptor beta-chain signaling controls immunosuppressive CD4+ T cells in the draining lymph nodes and lung during allergic airway inflammation in vivo. J Immunol. 2008;181(3): 1917-26
Zindler E, Gehrke N, Luft C, Reuter S, Taube C, Finotto S, Reske-Kunz AB, Sudowe S: (2008) Divergent effects of biolistic gene transfer in a mouse model of allergic airway inflammation. Am J Respir Cell Mol Biol. 2008;38(1): 38-46
Hausding M, Sauer K, Maxeiner JH, Finotto S: (2008) Transgenic models in allergic responses. Curr Drug Targets. 2008;9(6): 503-10
Karwot R, Maxeiner JH, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, Finotto S: (2008) Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model. J Allergy Clin Immunol. 2008;121(4): 992-9.e6
Presser K, Schwinge D, Wegmann M, Huber S, Schmitt S, Quaas A, Maxeiner JH, Finotto S, Lohse AW, Blessing M, Schramm C: (2008) Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity. J Immunol. 2008;181(11): 7751-8
Finotto S: (2008) T-cell regulation in asthmatic diseases. Chem Immunol Allergy. 2008;94(): 83-92
Maxeiner JH, Sauer K, Karwot R, Scholtes P, Wiewrodt R, Galle PR, Lehr HA, Finotto S: (2007) Increased lung tumor in NFATc2 (-/-) mice mediated by defective CD8+T cells and increased CD4+CD25+ lung T cells Cancer Immunol Immunother. 2007;56(3): 422-422
Sauer K, Maxeiner J, Scholtes P, Karwot R, Finotto S: (2007) EBI 3 deficient dendritic cells induce a CD8 mediated tumor cell death in a murine model of lung melanoma Cancer Immunol Immunother. 2007;56(3): 422-422
Randi ML, Scapin M, Finotto S, Scandellari R, Fabris E: (2007) No thrombopoietin (TPO) or its receptor (MPL) mutation in 6 families with myeloproliferative disorders Haematologica. 2007;92 Suppl. (): 1126 -
Maxeiner JH, Karwot R, Hausding M, Sauer KA, Scholtes P, Finotto S: (2007) A method to enable the investigation of murine bronchial immune cells, their cytokines and mediators. Nat Protoc. 2007;2(1): 105-12
Finotto S, Eigenbrod T, Karwot R, Boross I, Doganci A, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Galle PR, Neurath MF: (2007) Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells. Int Immunol. 2007;19(6): 685-93
Hausding M, Karwot R, Scholtes P, Lehr HA, Wegmann M, Renz H, Galle PR, Birkenbach M, Neurath MF, Blumberg RS, Finotto S: (2007) Lung CD11c+ cells from mice deficient in Epstein-Barr virus-induced gene 3 (EBI-3) prevent airway hyper-responsiveness in experimental asthma. Eur J Immunol. 2007;37(6): 1663-77
Caucig P, Dinges S, Teschner D, Maxeiner JH, Knop J, Finotto S, von Stebut E: (2006) Administration of proinflammatory interleukin-1 alpha during sensitization decreases T-helper 2-mediated allergic asthma Exp Dermatol. 2006;15(3): 189-189
Caucig P, Dinges S, Teschner D, Maxeiner JH, Knop J, Finotto S, von Stebut E: (2006) IL-1 alpha-mediated suppression of OVA-induced allergic asthma J Invest Dermatol. 2006;126 Suppl.(): 728 -
Caucig P, Dinges S, Maxeiner J, Finotto S, von Stebut E: (2006) IL-1 alpha suppresses Th2-mediated immune responses J Invest Dermatol. 2006;126 Suppl.(): 57-57
Sauer KA, Scholtes P, Karwot R, Finotto S: (2006) Isolation of CD4+ T cells from murine lungs: a method to analyze ongoing immune responses in the lung. Nat Protoc. 2006;1(6): 2870-5
Neurath MF, Finotto S: (2006) The many roads to inflammatory bowel diseases. Immunity. 2006;25(2): 189-91
Doganci A, Eigenbrod T, Krug N, De Sanctis GT, Hausding M, Erpenbeck VJ, Haddad E, Schmitt E, Bopp T, Kallen KJ, Herz U, Schmitt S, Luft C, Hecht O, Hohlfeld JM, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Renz H, Neurath MF, Galle PR, Finotto S: (2005) The IL-6R a chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo (vol 115, pg 1388, 2005) J Clin Invest. 2005;115(5): 1388-1388
Doganci A, Eigenbrod T, Krug N, De Sanctis GT, Hausding M, Erpenbeck VJ, Haddad el-B, Lehr HA, Schmitt E, Bopp T, Kallen KJ, Herz U, Schmitt S, Luft C, Hecht O, Hohlfeld JM, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Renz H, Neurath MF, Galle PR, Finotto S: (2005) The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J Clin Invest. 2005;115(2): 313-25
Finotto S, Hausding M, Doganci A, Maxeiner JH, Lehr HA, Luft C, Galle PR, Glimcher LH: (2005) Asthmatic changes in mice lacking T-bet are mediated by IL-13. Int Immunol. 2005;17(8): 993-1007
Doganci A, Sauer K, Karwot R, Finotto S: (2005) Pathological role of IL-6 in the experimental allergic bronchial asthma in mice. Clin Rev Allergy Immunol. 2005;28(3): 257-70
Doganci A, Neurath MF, Finotto S: (2005) Mucosal immunoregulation: transcription factors as possible therapeutic targets. Curr Drug Targets Inflamm Allergy. 2005;4(5): 565-75
Finotto S, Siebler J, Hausding M, Schipp M, Wirtz S, Klein S, Protschka M, Doganci A, Lehr HA, Trautwein C, Khosravi-Far R, Strand D, Lohse A, Galle PR, Blessing M, Neurath MF, Khosravi-Fahr R: (2004) Severe hepatic injury in interleukin 18 (IL-18) transgenic mice: a key role for IL-18 in regulating hepatocyte apoptosis in vivo. Gut. 2004;53(3): 392-400
Hausding M, Ho IC, Lehr HA, Weigmann B, Lux C, Schipp M, Galle PR, Finotto S: (2004) A stage-specific functional role of the leucine zipper transcription factor c-Maf in lung Th2 cell differentiation. Eur J Immunol. 2004;34(12): 3401-12
Finotto S, Glimcher L: (2004) T cell directives for transcriptional regulation in asthma. Springer Semin Immunopathol. 2004;25(3-4): 281-94
Luft C, Hausding M, Finotto S: (2004) Regulation of T cells in asthma: implications for genetic manipulation. Curr Opin Allergy Clin Immunol. 2004;4(1): 69-74
Huber S, Schramm C, Herz U, Protschka M, Burg J, Finotto S, Schmitt E, Galle PR, Blessing M: (2003) Transgenic mice overexpressing active TGF beta I in T-cells show altered T-cell development and resistance towards the induction of asthma FASEB J. 2003;17 Suppl. (7): C175-C175
Finotto S, Hausding M, Eigenbrod T, Herz U, Renz H: (2003) Molecular pathogenesis and immunotherapy of allergic asthma Rev Fr Allergol. 2003;26(1): 15-23
Schramm C, Herz U, Podlech J, Protschka M, Finotto S, Reddehase MJ, Köhler H, Galle PR, Lohse AW, Blessing M: (2003) TGF-beta regulates airway responses via T cells. J Immunol. 2003;170(3): 1313-9
Neurath M, Weigmann B, Finotto S, Glickman J, Nieuwenhuis EES, Iijima H, Mizoguchi A, Mizoguchi E, Bhan A, Galle PR, Sullivan B, Szabo SJ, Glimcher LH, Blumberg RS: (2002) The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohns disease Gastroenterology. 2002;122 Suppl.(4): 17 -
Neurath MF, Finotto S, Glimcher LH: (2002) The role of Th1/Th2 polarization in mucosal immunity. Nat Med. 2002;8(6): 567-73
Neurath MF, Weigmann B, Finotto S, Glickman J, Nieuwenhuis E, Iijima H, Mizoguchi A, Mizoguchi E, Mudter J, Galle PR, Bhan A, Autschbach F, Sullivan BM, Szabo SJ, Glimcher LH, Blumberg RS: (2002) The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med. 2002;195(9): 1129-43
Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH: (2002) Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science. 2002;295(5553): 336-8
Eigenbrod T, Buerke M, Schipp M, Herz U, Lehr HA, Atreja R, Kishimoto T, Renz H, Galle PR, Neurath MF, Finotto S: (2001) Local delivery of an anti-interleukin-6 receptor antibody suppresses lung inflammation, by induction of intrapulmonary cell apoptosis on a mouse model of asthma J Allergy Clin Immunol. 2001;107 Suppl.(2): 147 -
Finotto S, Lehr HA, Herz U, Buerke M, Schipp M, Schmitt E, Renz H, Galle PR, Neuruth MF: (2001) Treatment of allergic airway inflammation and hyper-responsiveness by antisense-induced local blockade of GATA-3 expression J Allergy Clin Immunol. 2001;107 Suppl.(2): 221 -
Finotto S, Buerke M, Lingnau K, Schmitt E, Galle PR, Neurath MF: (2001) Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthma. J Allergy Clin Immunol. 2001;107(2): 279-86
Finotto S, De Sanctis GT, Lehr HA, Herz U, Buerke M, Schipp M, Bartsch B, Atreya R, Schmitt E, Galle PR, Renz H, Neurath MF: (2001) Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression. J Exp Med. 2001;193(11): 1247-60
Neurath MF, Finotto S, Fuss I, Boirivant M, Galle PR, Strober W: (2001) Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question. Trends Immunol. 2001;22(1): 21-6
Finotto S, Atreya R, Blessing M, Galle PR, Neurath MF: (2000) Severe hepatic injury in interleukin-18 transgenic mice. Gastroenterology. 2000;118(4): 1206 -
Finotto S, Schurmann G, Galle PR, Mudter J, Neurath MF: (2000) Downregulation of the TH2 T cell associated transcription factors GATA-3 and NFA Tc1/2 in lamina propria T lymphocytes in Crohn's disease. Gastroenterology. 2000;118(4): 3627 -
Atreya R, Finotto S, Mudter J, Mullberg J, Jostock T, Holtmann M, Kishimoto T, Galle PR, Rose-John S, Neurath MF: (2000) Blockade of IL-6 transsignaling abrogates established experimental colitis in mice by suppression of T cell resistance against apoptosis. Gastroenterology. 2000;118(4): 4803 -
Finotto S, Buerke M, Lindau K, Atreya R, Wirtz S, Schmitt E, Galle PR, Neurath MF: (2000) Local administration of antisense phosphorothioate oligonucleotides to the C-Kit ligand, stem cell factor, abrogates airway inflammation and suppressed TH2 cytokine production in a murine model of asthma J Allergy Clin Immunol. 2000;105(1): 487 -
Finotto S, Schurmann G, Muller-Lobeck H, Mudter J, Galle PR, Neurath MF: (2000) Downregulation of the T helper 2 cytokine associated transcription factors GATA-3 and NFATc1/2 in T lymphocytes in Crohn's disease J Allergy Clin Immunol. 2000;105(1): 544 -
Atreya R, Mudter J, Finotto S, Mullberg J, Jostock T, Wirtz S, Schutz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schurmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF: (2000) Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo. Nat Med. 2000;6(5): 583-8
Finotto S, Galle PR, Neurath MF: (2000) [Immunopathogenesis of bronchial asthma]. Pneumologie. 2000;54(9): 412-8
Hildner K, Finotto S, Becker C, Schlaak J, Schirmacher P, Galle PR, Märker-Hermann E, Neurath MF: (1999) Tumour necrosis factor (TNF) production by T cell receptor-primed T lymphocytes is a target for low dose methotrexate in rheumatoid arthritis. Clin Exp Immunol. 1999;118(1): 137-46
Wirtz S, Finotto S, Kanzler S, Lohse AW, Blessing M, Lehr HA, Galle PR, Neurath MF: (1999) Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens. J Immunol. 1999;162(4): 1884-8
Finotto S, Krieglstein K, Schober A, Deimling F, Lindner K, Brühl B, Beier K, Metz J, Garcia-Arraras JE, Roig-Lopez JL, Monaghan P, Schmid W, Cole TJ, Kellendonk C, Tronche F, Schütz G, Unsicker K: (1999) Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999;126(13): 2935-44
Deimling F, Finotto S, Lindner K, Brühl B, Roig-Lopez JL, Garcia-Arraras JE, Goridis C, Krieglstein K, Unsicker K: (1998) Characterization of adrenal chromaffin progenitor cells in mice. Adv Pharmacol. 1998;42(): 932-5
Unsicker K, Finotto S, Krieglstein K: (1997) Generation of cell diversity in the peripheral autonomic nervous system: the sympathoadrenal cell lineage revisited. Ann Anat. 1997;179(6): 495-500
Finotto S, Mekori YA, METCALFE DD: (1997) Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems. J Clin Invest. 1997;99(7): 1721-8
Finotto S, Horowitz J, McLaren R, Busse PJ, METCALFE DD: (1996) Regulation of production of stem cell factor (SCF) by fibroblasts: Role of serum factors. J Allergy Clin Immunol. 1996;97(1): 396-396
Finotto S, MARSHALL JS, Butterfield JH, Denburg JA: (1996) Specific inhibition of beta-tryptase expression in a human mast cell line by granulocyte-macrophage colony-stimulating factor produced by airways structural cells. Am J Respir Cell Mol Biol. 1996;15(3): 355-60
LEA RG, UNDERWOOD J, FLANDERS KC, HIRTE H, BANWATT D, Finotto S, OHNO I, DAYA S, HARLEY C, MICHEL M, MOWBRAY JF, CLARK DA: (1995) A SUBSET OF PATIENTS WITH RECURRENT SPONTANEOUS-ABORTION IS DEFICIENT IN TRANSFORMING GROWTH-FACTOR BETA-2-PRODUCING SUPPRESSOR CELLS IN UTERINE TISSUE NEAR THE PLACENTAL ATTACHMENT SITE (VOL 34, PG 53, 1995) Am J Reprod Immunol. 1995;34(3): 208-208
Finotto S, OH CK, NAGATA H, METCALFE DD: (1995) EVIDENCE FOR TISSUE-SPECIFIC ALTERNATIVE SPLICING OF STEM-CELL FACTOR FASEB J. 1995;9(3): A488-A488
LEA RG, UNDERWOOD J, FLANDERS KC, HIRTE H, BANWATT D, Finotto S, OHNO I, DAYA S, HARLEY C, MICHEL M: (1995) A subset of patients with recurrent spontaneous abortion is deficient in transforming growth factor beta-2-producing "suppressor cells" in uterine tissue near the placental attachment site. Am J Reprod Immunol. 1995;34(1): 52-64
RAMIS I, Finotto S, DOLOVICH J, MARSHALL J, JORDANA M: (1995) Increased survival of nasal polyp eosinophils. Immunol Lett. 1995;45(3): 219-21
Finotto S, OHNO I, MARSHALL JS, Gauldie J, Denburg JA, DOLOVICH J, CLARK DA, JORDANA M: (1994) TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). J Immunol. 1994;153(5): 2278-89
Finotto S, DOLOVICH J, Denburg JA, JORDANA M, MARSHALL JS: (1994) Functional heterogeneity of mast cells isolated from different microenvironments within nasal polyp tissue. Clin Exp Immunol. 1994;95(2): 343-50
RAMIS I, Finotto S, DOLOVICH J, DENBURG J, GEARING D, JORDANA M: (1993) ENHANCED CONSTITUTIVE SURVIVAL OF NASAL POLYP-DERIVED EOSINOPHILS EXVIVO - ROLE OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) Am Rev Respir Dis. 1993;147 Suppl.(4): A821-A821
Finotto S, RAMIS I, DOLOVICH J, DENBURG J, MARSHALL JS, JORDANA M: (1993) ISOLATION OF AN ENRICHED ACTIVATED EOSINOPHIL (E-PHI) FRACTION FROM HUMAN NASAL POLYP (NP) TISSUES J Allergy Clin Immunol. 1993;91(1): 157-157
Finotto S, Rado V, Dal Vecchio A, Milani G, Fabbri LM, Maestrelli P: (1993) Identification of epithelial cells in bronchoalveolar lavage. Hum Exp Toxicol. 1993;12(1): 43-6
Finotto S, MARSHALL JS, IRANI A, SCHWARTZ L, BUTTERFIELD J, OHNO I, DOLOVICH J, JORDANA M, DENBURG J: (1992) THE EFFECT OF NASAL POLYP STRUCTURAL CELL CONDITIONED MEDIA ON MAST-CELL MEDIATOR EXPRESSION FASEB J. 1992;6(5): A1723-A1723
Finotto S, MARSHALL J, IRANI A, SCHWARTZ L, BUTTERFIELD J, OHNO I, DOLOVICH J, JORDANA M, DENBURG J: (1992) REGULATION OF PROTEASE AND CYTOKINE EXPRESSION IN A HUMAN MAST-CELL LINE (HMC-1) - EFFECT OF NASAL POLYP STRUCTURAL CELL-DERIVED CONDITIONED MEDIA J Allergy Clin Immunol. 1992;89(1): 246-246
DENBURG J, DOLOVICH J, KANAI N, Finotto S, OHNO I, MARSHALL J, JORDANA M: (1992) MICROENVIRONMENTAL CONTROL OF INFLAMMATORY CELL-DIFFERENTIATION Int Arch Allergy Immunol. 1992;99(2-4): 330-332
OHNO I, Lea R, Finotto S, MARSHALL J, DENBURG J, DOLOVICH J, Gauldie J, JORDANA M: (1991) Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis. Am J Respir Cell Mol Biol. 1991;5(6): 505-10
Finotto S, Fabbri LM, Rado V, Mapp CE, Maestrelli P: (1991) Increase in numbers of CD8 positive lymphocytes and eosinophils in peripheral blood of subjects with late asthmatic reactions induced by toluene diisocyanate. Br J Ind Med. 1991;48(2): 116-21
BELLI M, CHERUBINI R, Finotto S, MOSCHINI G, SAPORA O, SIMONE G, TABOCCHINI MA: (1989) RBE-LET relationship for the survival of V79 cells irradiated with low energy protons. Int J Radiat Biol. 1989;55(1): 93-104
Chitano P, Di Stefano A, Finotto S, Zavattini G, Maestrelli P, Mapp C, Fabbri LM, Allegra L: (1989) Ambroxol inhibits airway hyperresponsiveness induced by ozone in dogs. Respiration. 1989;55 Suppl 1(): 74-8
BELLI M, CHERUBINI R, Finotto S, MOSCHINI G, SAPORA O, SIMONE G, TABOCCHINI MA: (1987) INACTIVATION OF CHINESE-HAMSTER V79 CELLS BY HIGH LET PROTON-BEAMS Int J Radiat Biol. 1987;51(5): 931-932
Sarto F, Finotto S, Giacomelli L, Mazzotti D, Tomanin R, Levis AG: (1987) The micronucleus assay in exfoliated cells of the human buccal mucosa. Mutagenesis. 1987;2(1): 11-7

Schriftgröße anpassen

Notfall

Notfallinformationen UKER

Forschung

Lehre

Über uns

Aktuelles