Our department is interested to study the Immunopathogenesis of allergic bronchial asthma and the bronchial carcinoma as well as lung metastases. In this field it is our main aim to understand the immunological responses present in these diseases to set up new therapies.
Our special interest is the expression of transcription factors and the study of pro- and anti-inflammatory cytokine production as well as the modulation of inflammatory responses through neutralizing cytokine antibodies. Especially, our group is analysing the expression and function of T-cell-associated transcription factors, like T-bet, NFAT, BATF, RORgT, NIP45, NFATc1, c-maf and GATA-3. Additionally we analyse effector-, memory- and regulatory T-cell-subsets.